Suicide is the act of willingly ending one's own life.
- Marcus Dixon: After his wife's death, Marcus went into a deep depression and almost killed himself by jumping off a bridge, but at the last moment he changed his mind.
- Nancy Cahill: While hallucinating on a drug, Nancy went insane and thought people were chasing her. With no other option, Nancy shot herself in the chin.
- Korjev hitman: In order to prevent capture from the APO (and to save his family) a hitman sent by Sasha Korjev slit his throat.
- Ivan Curtis: Knowing that Prophet 5 would kill him anyway for his failure, Curtis jumped out of a plane hundreds of thousands of feet in the air.
- Gordon Dean: In order to save his daughter, Sloane forced Dean to swallow a suicide capsule, making his death look like a suicide.
- Jack Bristow: Near death, Jack climbed inside Rambaldi's Tomb with a bomb belt in his hands, encountering Sloane. Jack sacrificed himself by blowing up the bomb and sealing Sloane inside the temple, making sure Sloane could never hurt his daughter again.